Adrianna Mostowska

ORCID: 0000-0003-4181-9402 · 9 papers in corpus
article 2018
The assessment of GWAS — identified polymorphisms associated with infertility risk in Polish women with endometriosis
Ginekologia polska ·doi:10.5603/gp.a2018.0052

OBJECTIVES: Genome-wide association studies in patients with endometriosis revealed ten significant single nucleo-tide polymorphisms (SNPs) in the Caucasian population, which include rs12700667 near NFE2L3, rs12037376 in WNT4, rs7521902 nea…

other 2017
Involvement of 17β-hydroxysteroid dehydrogenase type gene 1 937 A>G polymorphism in infertility in Polish Caucasian women with endometriosis
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-017-0911-9

PURPOSE: Endometriosis is considered to be an estrogen-related chronic inflammatory disease. The 17β-hydroxysteroid dehydrogenase 1 (HSD17B1) converts estrone to 17β estradiol. The role of HSD17B1 937 A>G (rs605059) single nucleotide polymo…

article 2015
Association between DNMT3L polymorphic variants and the risk of endometriosis-associated infertility
Molecular medicine reports ·doi:10.3892/mmr.2015.4626

Endometriosis is considered to be an epigenetic disease. It has previously been reported that the DNA methyltransferase 3-like (DNMT3L) rs8129776 single nucleotide polymorphism (SNP) contributes to endometrioma. In the present study, high‑r…

other 2015
Involvement of vascular endothelial growth factor -460 C/T, +405 G/C and +936 C/T polymorphisms in the development of endometriosis
Biomedical reports ·doi:10.3892/br.2014.409

There are inconsistent data on the contribution of vascular endothelial growth factor (VEGF) -460 C/T (rs833061), +405 G/C (rs2010963) and +936 C/T (rs3025039) single-nucleotide polymorphisms (SNPs) to endometriosis in different ethnicities…

article 2015
Polymorphic variants in the dopamine receptor D2 in women with endometriosis-related infertility
Molecular medicine reports ·doi:10.3892/mmr.2015.3733

Data suggests that dopamine receptor DRD2 gene variants may contribute to hyperprolactinemia and that they may be risk factors for endometriosis-related infertility. The purpose of the present study was to determine whether nucleotide varia…

article 2015
Polymorphic variants in vitamin D signaling pathway genes and the risk of endometriosis-associated infertility
Molecular medicine reports ·doi:10.3892/mmr.2015.4309

It has recently been reported that vitamin D blood plasma levels are associated with reduced risk of endometriosis. The present study aimed to investigate whether the vitamin D binding protein (GC), vitamin D receptor (VDR), and retinoid X …

2015
Replication study for the association of seven genome- GWAS-identified Loci with susceptibility to ovarian cancer in the Polish population.
Pathology oncology research : POR ·doi:10.1007/s12253-014-9822-6

We investigated the previously-demonstrated association of seven genome-wide association studies (GWAS) single nucleotide polymorphisms (SNPs), including rs2072590 (HOXD-AS1), rs2665390 (TIPARP), rs10088218 and rs10098821 (8q24), rs3814113 …

article 2012
Polymorphic variants of DNMT3A and the risk of endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2012.09.003

ObjectiveOverexpression of DNA methyltransferase 3A (DNMT3A) and aberrant methylation of various genes in eutopic endometrium have been demonstrated in women with endometriosis. We aimed to study whether DNMT3A polymorphisms could be a gene…

article 2011
Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2011.02.003

ObjectiveEndometriosis has been considered an epigenetic disease. Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity.Study designWe studied…