R J Santen

No ORCID on file · 2 papers in corpus
other 1985
Annals of internal medicine ·doi:10.7326/0003-4819-102-5-643

The chemical structure of luteinizing-hormone-releasing hormone (LHRH) was discovered in 1971 after more than a decade of intensive effort. Subsequent physiologic studies in primates and humans showed that the biologic activity of LHRH depe…

nonrandomized-trial 1983
The Journal of clinical investigation ·doi:10.1172/jci110940

Potent synthetic analogs of gonadotropin-releasing hormone produce parodoxical antireproductive effects when administered chronically. These compounds are minimally toxic and may exhibit no plateau of the dose-response curve even at very hi…