Siomara Hernández

We previously demonstrated the negative impact of stress in an animal model of endometriosis. Although its role is unclear, altered levels of vitamin D (VitD) have been found in patients with this condition. VitD signaling through the VitD …

PurposePain in patients with endometriosis is considered a significant source of stress but does not always correlate with severity of the condition. We have demonstrated that stress can worsen endometriosis in an animal model. Here, we tes…

Studies have examined how endometriosis interacts with the nervous system, but little attention has been paid to opioidergic systems, which are relevant to pain signaling. We used the autotransplantation rat model of endometriosis and allow…

Although the role of vitamin D in endometriosis is still unclear, vitamin D signaling through the vitamin D receptor (VDR) is associated with anti‐proliferative and anti‐inflammatory effects. We previously reported differential VDR expressi…

Prior studies from our laboratory have shown that stress can exacerbate the severity of endometriosis, a chronic gynecological disorder. The vitamin D receptor (VDR), expressed in cycling endometrium, is associated with anti-proliferative a…

BACKGROUND: Symptoms of endometriosis, such as pain and infertility, are considered significant sources of stress. In many chronic conditions, exercise can act as a stress buffer and influence pain perception. We tested the impact of swimmi…

Endometriosis is characterized by peritoneal inflammation, infertility and chronic pelvic pain that substantially affect quality of life. Since stress can affect the immune system and recruitment of inflammatory cells it may contribute to t…

We have previously shown detrimental effects of stress in an animal model of endometriosis. We now investigated whether the ability to control stress can affect disease parameters. Endometriosis was surgically induced in female Sprague-Dawl…

Endometriosis is a debilitating disease characterized by pelvic pain, dysmenorrhea and dyspareunia. These symptoms produce stress on the individual and impact daily life activities. It is still poorly understood how stress affects endometri…

The uterus is composed of smooth muscle layers allowing its regulation. Endometriosis is defined as the presence of endometrium‐like tissue outside the uterus and is characterized by peritoneal inflammation, cysts, adhesions, infertility an…