Zhiyuan Jin

No ORCID on file · 1 paper in corpus

2022

Homology-Directed Repair of an MYBPC3 gene mutation in a rat model of hypertrophic cardiomyopathy

·doi:10.21203/rs.3.rs-2199328/v1

Abstract Variants in myosin-binding protein C3 (MYBPC3) gene are a main cause of hypertrophic cardiomyopathy (HCM), accounting for 30–40% of the total number of HCM cases. Gene editing represents a potential permanent cure for HCM. The aim…