Kennedy BK

ORCID: 0000-0002-5754-1874 · 1 paper in corpus

2015

MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.

Mutation research ·doi:10.1016/j.mrfmmm.2015.04.010

Zmpste24 is a metalloproteinase responsible for the posttranslational processing and cleavage of prelamin A into mature laminA. Zmpste24(-/-) mice display a range of progeroid phenotypes overlapping with mice expressing progerin, an altered…