Cristina R. Antonescu

ORCID: 0000-0002-9717-8205 · 3 papers in corpus
2023
Expanding the molecular spectrum of gene fusions in endometrial stromal sarcoma: Novel subunits of the chromatin remodeling complexes PRC2 and NuA4/TIP60 as alternative fusion partners.
Genes, chromosomes & cancer ·doi:10.1002/gcc.23109

Endometrial stromal sarcomas (ESS) are morphologically and molecularly heterogeneous. We report novel gene fusions (EPC1::EED, EPC1::EZH2, ING3::PHF1) identified by targeted RNA sequencing in five cases. The ING3::PHF1-fusion positive ESS p…

article 2022
A novel WWTR1::AFF2 fusion in an intra‐abdominal soft tissue sarcoma with associated endometriosis
Genes, chromosomes & cancer ·doi:10.1002/gcc.23045

Application of molecular testing in clinical practice has led to significant advances in the classification of soft tissue sarcomas. Despite remarkable progress, there are still challenging cases that remain unclassified. In this study, we …

2022
Low-grade endometrial stromal sarcoma-like tumors in male with JAZF1 gene fusions.
Genes, chromosomes & cancer ·doi:10.1002/gcc.23003

Low-grade endometrial stromal sarcoma (ESS) is a hormone-responsive low-grade sarcoma typically occurring in the uterine corpus in women. Their genetic hallmarks are recurrent gene fusions involving JAZF1, partnering with either SUZ12 gene …