A Johns

No ORCID on file · 4 papers in corpus · active 1996-2000

Study types

  • article 3
  • review 1

Condition tags

  • endometriosis 4
article 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.85.8.2897

We previously demonstrated that 17beta hydroxysteroid dehydrogenase type 2, the enzyme that inactivates estradiol to estrone, is expressed in luteal eutopic endometrium in response to progesterone but not in simultaneously biopsied peritone…

review 1999
Endocrine-related cancer ·doi:10.1677/erc.0.0060293

Estrogen is the most important known factor that stimulates the growth of endometriosis. Estrogen delivery to endometriotic implants was classically viewed to be only via the circulating blood in an endocrine fashion. We recently uncovered …

article 1998
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.83.12.5301

Aberrant aromatase expression in stromal cells of endometriosis gives rise to conversion of circulating androstenedione to estrone in this tissue, whereas aromatase expression is absent in the eutopic endometrium. In this study, we initiall…

article 1996
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.81.1.8550748

The conversion of C19 steroids to estrogens occurs in a number of tissues, such as the ovary and placenta, and is catalyzed by aromatase P450 (P450arom; the product of the CYP19 gene). P450arom expression has also been detected in a number …