Kazuhiro Takehara

ORCID: 0000-0001-8808-3338 · 4 papers in corpus
nonrandomized-trial 2024
A phase II trial evaluating the efficacy and safety of repeated high dose medroxyprogesterone acetate (MPA) therapy for patients with recurrent early-stage endometrial cancer or atypical endometrial hyperplasia: Japanese Gynecologic Oncology Group study (JGOG2051/KGOG2031, REMPA trial)
Journal of gynecologic oncology ·doi:10.3802/jgo.2024.35.e106

BACKGROUND: Fertility preserving therapy using medroxyprogesterone acetate (MPA) is an important option for young patients with endometrial cancer or atypical endometrial hyperplasia (AEH). However, the effectiveness and feasibility of repe…

case-report 2022
Laparoscopic Triple Segmental Bowel Resection for Endometriosis Revealed by Rectal Obstruction during Infertility Treatment
Case reports in gastroenterology ·doi:10.1159/000521941

Intestinal endometriosis is a benign disease characterized by ectopic growth of the endometrium and causes extensive fibrosis and adhesions in response to repeated episodes of bleeding and inflammation with the menstrual cycle. We encounter…

nonrandomized-trial 2020
Pembrolizumab monotherapy in Japanese patients with advanced ovarian cancer: Subgroup analysis from the KEYNOTE-100
Cancer science ·doi:10.1111/cas.14340

Interim results from the two-cohort, phase 2 KEYNOTE-100 study (NCT02674061) of 376 patients with previously treated advanced recurrent ovarian cancer (ROC) showed that pembrolizumab monotherapy was associated with an objective response rat…

case-report 2014
A case of clear cell adenocarcinoma arising from endometriosis of the rectum treated by laparoscopic surgery
International journal of surgery case reports ·doi:10.1016/j.ijscr.2014.10.034

INTRODUCTION: Malignant transformation of intestinal endometriosis occurring in the extraovarian sites is extremely rare. We report a very rare case of clear cell adenocarcinoma arising from endometriosis of the rectum. PRESENTATION OF CAS…