Birt JA

No ORCID on file · 5 papers in corpus
2020
Corticosteroid dosing and opioid use are high in patients with SLE and remain elevated after belimumab initiation: a retrospective claims database analysis.
Lupus science & medicine ·doi:10.1136/lupus-2020-000435

ObjectivesTo investigate corticosteroid and opioid use among patients with SLE and to examine the impact of belimumab initiation on the use of other SLE therapies.MethodsWe identified adult patients with SLE (International Classification of…

article 2013
Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first-generation and second-generation embryos
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.07.007

ObjectiveTo characterize multigenerational gene expression anomalies in eight-cell stage embryos associated with developmental exposure to endometriosis.DesignUsing an endometriosis model in rats (F0 founder generation) to evaluate gene exp…

article 2013
Elevated Peritoneal Fluid TNF-α Incites Ovarian Early Growth Response Factor 1 Expression and Downstream Protease Mediators: A Correlation With Ovulatory Dysfunction in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113477479

Endometriosis-associated infertility manifests itself via multiple, poorly understood mechanisms. Our goal was to characterize signaling pathways, between peritoneal endometriotic lesions and the ovary, leading to failed ovulation. Genome-w…

other 2010
Inflammatory cytokines differentially up-regulate human endometrial haptoglobin production in women with endometriosis
Human Reproduction ·doi:10.1093/humrep/deq032

BACKGROUND: Evidence suggests that eutopic endometrium from women with endometriosis (US-E) has intrinsic functional anomalies compared with women without endometriosis (US-C). We hypothesized that differences in endometrial haptoglobin (eH…

other 2010
Neutralizing TIMP1 restores fecundity in a rat model of endometriosis and treating control rats with TIMP1 causes anomalies in ovarian function and embryo development
Biology of reproduction ·doi:10.1095/biolreprod.109.083287

Human and rat endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase 1 (TIMP1). More TIMP1 localizes in the ovarian theca in an established rat model for endometriosis (Endo) when compared to surgical controls (S…