Kadriye Nilay Özcan

ORCID: 0000-0002-5270-5630 · 1 paper in corpus

article 2025

Vortioxetine protects against methotrexate-induced ovarian toxicity through anti-inflammatory, antioxidant and antiapoptotic pathways: a multi-marker immunohistochemical study

·doi:10.1007/s10735-025-10642-w

AimsMethotrexate (MTX), a commonly used chemotherapeutic and immunosuppressive agent, is known to induce significant ovarian toxicity through mechanisms involving oxidative stress, inflammation, and apoptosis. Vortioxetine (VTX), a novel an…