Herbst-Kralovetz MM

No ORCID on file · 7 papers in corpus · active 2022-2025

Study types

  • article 1

Condition tags

  • endometriosis 1
  • chronic_pelvic_pain 1
  • irritable_bowel_syndrome 1
  • endometrioma 1
2025
Metabolic comparison of minimally to noninvasive urogenital sample types for studying gynecologic health: A pilot study.
iScience ·doi:10.1016/j.isci.2025.112938

In this pilot study, we investigated three minimally to noninvasive biospecimens: cervicovaginal lavages (CVLs), vaginal swabs, and urine, from 18 premenopausal women using untargeted metabolomics to inform future gynecologic research. Meta…

2025
Navigating complexities of polymorphic microbiomes in endometrial cancer.
NPJ biofilms and microbiomes ·doi:10.1038/s41522-025-00690-1

The microbiome is key to understanding endometrial cancer (EC) etiology and prevention strategies, implicated in the regulation of estrogen in estrogen-driven cancers. Utilizing robust methodologies in the QIIME 2 platform, we examined 16S …

2024
Cervicovaginal lavages uncover growth factors as key biomarkers for early diagnosis and prognosis of endometrial cancer.
Molecular biomedicine ·doi:10.1186/s43556-024-00219-6

Endometrial cancer (EC) rates are continuing to rise and it remains the most common gynecologic cancer in the US. Existing diagnostic methods are invasive and can cause pain and anxiety. Hence, there is a need for less invasive diagnostics …

article 2024
Vaginal and rectal microbiome contribute to genital inflammation in chronic pelvic pain
BMC medicine ·doi:10.1186/s12916-024-03500-1

BACKGROUND: Chronic pelvic pain (CPP) is a multifactorial syndrome that can substantially affect a patient's quality of life. Endometriosis is one cause of CPP, and alterations of the immune and microbiome profiles have been observed in pat…

2023
COVID-19 vaccination and changes in the menstrual cycle among vaccinated persons.
Fertility and sterility ·doi:10.1016/j.fertnstert.2022.12.023

ObjectiveTo describe the characteristics of people who experience changes to their menstrual cycle after COVID-19 vaccination.DesignLongitudinal study.Patient(s)We recruited a volunteer sample with and without a history of SARS-CoV-2 infect…

2023
Preoperative quality of life at time of gynecologic surgery: considerations for postoperative management.
AJOG global reports ·doi:10.1016/j.xagr.2023.100275

BackgroundPatients presenting for gynecologic surgery are a heterogeneous group. Preoperative quality of life may be a useful tool to guide postoperative management.ObjectiveThis study aimed to examine the key drivers of preoperative qualit…

2022
Protein biomarkers in cervicovaginal lavages for detection of endometrial cancer.
Biomarker research ·doi:10.1186/s40364-022-00438-5

BackgroundRates of endometrial cancer (EC) are increasing. For a definitive diagnosis, women undergo various time-consuming and painful medical procedures, such as endometrial biopsy with or without hysteroscopy, and dilation and curettage,…