Ruud L.M. Bekkers

ORCID: 0000-0002-4577-8495 · 15 papers in corpus
article 2026
·doi:10.1016/j.ijgc.2025.102918
article 2025
Human pathology ·doi:10.1016/j.humpath.2025.105875

OBJECTIVE: - Atypical endometriosis (AE) is considered a potential precursor of endometriosis-associated ovarian carcinoma (EAOC). Despite this, AE identification currently lacks established clinical implications and is not routinely incorp…

preprint 2025
·doi:10.2139/ssrn.5263731
article 2024
·doi:10.1136/ijgc-2024-esgo.1131
article 2024
·doi:10.1136/ijgc-2024-esgo.632
2022
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.14306

IntroductionThe local environment of the fallopian tube represents the optimal conditions for reproductive processes. To maintain tissue homeostasis, signal transduction pathways are thought to play a pivotal role. Enhancing our understandi…

article 2022
Fertility and sterility ·doi:10.1016/j.fertnstert.2022.01.030

ObjectiveTo assess the incidence of ovarian cancer in women with histologically proven endometriosis after bilateral salpingo-oophorectomy (BSO).DesignRetrospective nationwide cohort study.SettingDutch pathology database.Patient(s)Women wit…

article 2021
Cancers ·doi:10.3390/cancers13184592

Women with histologically proven endometriosis/adenomyosis have an increased risk of ovarian cancer. Small studies show conflicting results on the endometrial cancer risk in women with endometriosis/adenomyosis. Therefore, we assessed the i…

article 2021
International journal of cancer ·doi:10.1002/ijc.33907

We aim to compare endometrial cancer survival in women with or without histological proven endometriosis or adenomyosis. We identified all women with endometrial cancer between 1990 and 2015 from the Netherlands Cancer Registry (NCR). Data …

review 2021
Cancer Immunology, Immunotherapy ·doi:10.1007/s00262-020-02831-1

IntroductionEndometriosis is a risk factor for low-grade serous, clear cell, and endometroid ovarian carcinoma. In both endometriosis and ovarian carcinoma, immunological factors are associated with clinical outcome. Chronic inflammation in…

article 2021
Gynecologic Oncology ·doi:10.1016/j.ygyno.2021.07.006

ObjectiveAssessing the association between endometriosis and/or adenomyosis and ovarian cancer.MethodsWe identified all women with histological proven endometriosis (51,544 women) and/or adenomyosis (85,015 women) from the Dutch pathology d…

article 2020
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2020.01.041

BackgroundSeveral studies have suggested that endometriosis is associated with an increased risk of ovarian cancer, especially for the clear-cell and endometrioid subtypes. However, previous studies lack sufficient power or diagnostic certa…

article 2020
Cancer epidemiology ·doi:10.1016/j.canep.2020.101700

BackgroundFew studies have investigated the possible association between endosalpingiosis and ovarian cancer, therefore we assessed whether there is an association between histological confirmed endosalpingiosis and ovarian cancer.MethodsWe…

article 2020
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2020.08.056

BackgroundContradicting results regarding ovarian cancer prognosis in women with endometriosis have been reported in the literature. Owing to the small sample size of previous studies, larger studies are required to elucidate the role of en…

article 2019
·doi:10.1136/ijgc-2019-esgo.1276