CheMyong Ko

ORCID: 0000-0002-0963-3731 · 5 papers in corpus
lab-animal 2025
Endocrinology ·doi:10.1210/endocr/bqaf006

This study uncovers a dynamic shift in estrogen receptor expression during granulosa cell (GC) differentiation in the ovary, highlighting a transition from estrogen receptor alpha (ESR1) to estrogen receptor beta (ESR2). Using a transgenic …

review 2019
Endocrine Reviews ·doi:10.1210/er.2018-00075

The midcycle surge of LH sets in motion interconnected networks of signaling cascades to bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators of these LH-induced signaling cascades are associated wi…

lab-animal 2015
Science translational medicine ·doi:10.1126/scitranslmed.3010626

Estrogenic and inflammatory components play key roles in a broad range of diseases including endometriosis, a common estrogen-dependent gynecological disorder in which endometrial tissue creates inflammatory lesions at extrauterine sites, c…

lab-animal 2012
Endocrinology ·doi:10.1210/en.2011-1900

Oviductal disease is a primary cause of infertility, a problem that largely stems from excessive inflammation of this key reproductive organ. Our poor understanding of the mechanisms regulating oviductal inflammation restricts our ability t…

other 2011
Human reproduction (Oxford, England) ·doi:10.1093/humrep/der066

BACKGROUND: Whether ovarian follicular rupture involves contractile activity or not has been debated for decades. Recently, study in the rodents has indicated that an endogenously produced potent vasoconstrictive peptide, endothelin-2 (EDN2…