Nigel W Bunnett

No ORCID on file · 3 papers in corpus
review 2026
Engineering Nanoscale Drug Delivery Systems for Pain
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology ·doi:10.1002/wnan.70072

Pain is a pervasive and multifaceted condition that imposes a significant medical and economic burden worldwide. This burden is underscored by the urgent need for transformative, non-addictive opioid alternatives. Nanomedicine offers a prom…

lab-animal 2023
Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors
Pain ·doi:10.1097/j.pain.0000000000002970

Neuropilin-1 (NRP-1) is a transmembrane glycoprotein that binds numerous ligands including vascular endothelial growth factor A (VEGFA). Binding of this ligand to NRP-1 and the co-receptor, the tyrosine kinase receptor VEGFR2, elicits nocic…

lab-animal 2016
Legumain is activated in macrophages during pancreatitis
American journal of physiology. Gastrointestinal and liver physiology ·doi:10.1152/ajpgi.00047.2016

Pancreatitis is an inflammatory disease of the pancreas characterized by dysregulated activity of digestive enzymes, necrosis, immune infiltration, and pain. Repeated incidence of pancreatitis is an important risk factor for pancreatic canc…