Hongyan Guo

ORCID: 0000-0001-6917-5341 · 9 papers in corpus · active 2015-2026

Study types

  • article 5
  • preprint 2
  • other 1
  • rct 1

Condition tags

  • adenomyosis 7
  • mesh:D004715 4
  • dysmenorrhea 4
  • mesh:D004412 4
  • endometriosis 3
  • infertility 2
  • mesh:D017699 1
  • endometrioma 1
  • die_deep_infiltrating 1
other 2026
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis
EBioMedicine ·doi:10.1016/j.ebiom.2026.106225

BACKGROUND: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has been widely applied in oncology but remains underexplored for adenomyosis. We aimed to identi…

preprint 2025
5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Serve as Potential Biomarkers for Diagnosis and Classification of Adenomyosis
·doi:10.2139/ssrn.5163331
article 2025
Clinical features and perinatal outcomes in women with adenomyosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.114631
preprint 2023
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis
·doi:10.21203/rs.3.rs-3253918/v1

Abstract Background: At present, clinical diagnosis and classification of adenomyosis are mainly dependent on MRI or pathological examination, and little research is carried out on molecular biomarkers for the diagnosis and classification o…

article 2023
[Analysis of the relationship between MRI imaging characteristics and clinical symptoms and therapeutic efficacy in adenomyosis patients].
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20221130-00727

Concomitant ovarian endometrioma increases the risk of dysmenorrhea in patients with adenomyosis. The ratio of the maximum lesion thickness to the maximum myometrium thickness is an independent risk factor for menorrhagia. Young and large u…

article 2023
Heterogeneity of clinical symptoms and therapeutic strategies for different subtypes of adenomyosis: An initial single‐center study in China
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.14650

OBJECTIVE: To investigate the relationship between the magnetic resonance imaging (MRI) classification of different clinical symptoms and corresponding therapeutic efficacy in adenomyosis patients. METHODS: From January 2015 to October 2020…

rct 2023
Safety, Pharmacokinetics, and Pharmacodynamics of SHR7280, a Non-peptide GnRH Antagonist in Premenopausal Women with Endometriosis: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
Clinical pharmacokinetics ·doi:10.1007/s40262-023-01315-6

BACKGROUND: Oral gonadotropin-releasing hormone (GnRH) antagonists are promising agents in the treatment of endometriosis-related pain. Here we assessed the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of SHR7280, an oral non-pe…

article 2017
[Role of oral contraceptives in preventing endometriosis-related pain progression].
Zhonghua yi xue za zhi ·doi:10.3760/cma.j.issn.0376-2491.2017.39.012

Endometriosis is a progressing disease. Longterm medication of oral contraceptives can relieve the dysmenorrhea pain.The extent of pain relief was not connected with the length of medication.Dysmenorrhea recurred after quitting medication, …

article 2015
[Relationship between endometriosis stage, characteristics of enodmetriotic lesions and severity of dysmenorrhoea].
Zhonghua yi xue za zhi

OBJECTIVE: To explore the association between endometriosis stage, characteristics of endometriotic lesions and severity of dysmenorrhoea. METHODS: The clinical data were collected from 140 patients with laparoscopically diagnosed endometri…