Hongyan Guo

ORCID: 0000-0001-6917-5341 · 15 papers in corpus
diagnostic-accuracy 2026
EBioMedicine ·doi:10.1016/j.ebiom.2026.106225

BACKGROUND: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has been widely applied in oncology but remains underexplored for adenomyosis. We aimed to identi…

2025
·doi:10.2139/ssrn.5163331
observational 2025
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.114631

OBJECTIVE: To analyze the correlation between Clinical Features and Perinatal Outcomes in the population of pregnancies with adenomyosis. METHODS: This retrospective study analyzed 413 pregnant women with ultrasonography/MRI-confirmed aden…

diagnostic-accuracy 2023
·doi:10.21203/rs.3.rs-3253918/v1

Abstract Background: At present, clinical diagnosis and classification of adenomyosis are mainly dependent on MRI or pathological examination, and little research is carried out on molecular biomarkers for the diagnosis and classification o…

observational 2023
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.cn112141-20221130-00727

Objective: To investigate the relationship between magnetic resonance imaging (MRI) imaging characteristics and clinical symptoms and therapeutic efficacy in adenomyosis patients. Methods: The clinical characteristics of the adenomyosis que…

observational 2023
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.14650

OBJECTIVE: To investigate the relationship between the magnetic resonance imaging (MRI) classification of different clinical symptoms and corresponding therapeutic efficacy in adenomyosis patients. METHODS: From January 2015 to October 202…

other 2023
Cancer medicine ·doi:10.1002/cam4.5643

INTRODUCTION: Stage IB (deep myometrial invasion) high-grade endometrioid adenocarcinoma (EA), regardless of LVSI status, is classified into high-intermediate risk groups, requiring surgical lymph node staging. Intraoperative frozen section…

rct 2023
Clinical pharmacokinetics ·doi:10.1007/s40262-023-01315-6

BACKGROUND: Oral gonadotropin-releasing hormone (GnRH) antagonists are promising agents in the treatment of endometriosis-related pain. Here we assessed the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of SHR7280, an oral non-pe…

other 2022
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu ·doi:10.21147/j.issn.1000-9604.2022.02.04

OBJECTIVE: Emerging studies have demonstrated the promising clinical value of circulating tumor cells (CTCs) for diagnosis, disease assessment, treatment monitoring and prognosis in epithelial ovarian cancer. However, the clinical applicati…

observational 2022
Medicine ·doi:10.1097/md.0000000000031369

To assess the clinical value of microcystic, elongated, and fragmented (MELF) pattern in Chinese patients with endometrial endometrioid carcinoma. A total of 189 patients with endometrial endometrioid carcinoma were retrospectively analyzed…

other 2021
BioMed research international ·doi:10.1155/2021/4804694

Endometrial carcinoma (EC) is the fifth widely occurring malignant neoplasm among women all over the world. However, there is still lacking efficacy indicators for EC's prognosis. Here, we analyzed two databases including an RNA-sequencing-…

lab-animal 2020
PloS one ·doi:10.1371/journal.pone.0243140

OBJECTIVE: This study examined the feasibility and safety of allogeneic uterus transplantation (UTx) from a living donor and assessed short-term graft viability in a rhesus model. This research is an important step towards further clinical …

review 2020
Annals of translational medicine ·doi:10.21037/atm.2020.02.53

Adhesion is a postoperative complication that has plagued gynecologists for many years, as 60-90% of gynecological patients develop adhesions after abdominopelvic surgeries. Abdominopelvic adhesions could lead to chronic pelvic pain, infert…

nonrandomized-trial 2017
Zhonghua yi xue za zhi ·doi:10.3760/cma.j.issn.0376-2491.2017.39.012

Objective: To analyze the effect of oral contraceptives on dysmenorrhea in patients with endometriosis. Methods: We designed dysmenorrhea and chronic pelvic pain questionnaire.From February 2014 to February 2016 in the Gynecological Departm…

observational 2015
Zhonghua yi xue za zhi

OBJECTIVE: To explore the association between endometriosis stage, characteristics of endometriotic lesions and severity of dysmenorrhoea. METHODS: The clinical data were collected from 140 patients with laparoscopically diagnosed endometr…