Jorge E Chavarro

OBJECTIVE: To evaluate the quality of remote semen collection and a smartphone-based semen analysis system under real-world conditions compared with a laboratory assessment among participants who were unselected for fertility status. DESIG…

OBJECTIVE: Disordered eating behaviors may impact the gynecologic health of adolescents through effects on menstrual cycle function and body size; however, few studies have evaluated these associations. This study aimed to prospectively inv…

BACKGROUND: Longitudinal studies suggest that diets encouraging higher intake of fruits and vegetables and lower intake of red meat are associated with a lower risk of laparoscopically-confirmed endometriosis. However, no studies have exami…

INTRODUCTION: There is increasing evidence that women who have experienced infertility are at greater risk for several chronic conditions. However, the mechanisms underlying these associations are not clear. Pathophysiology may be illuminat…

BackgroundApproximately 1 in 3 pregnancies in the United States are complicated by one or more adverse pregnancy outcomes. This high prevalence contributes to the elevated rates of maternal and infant mortality in the United States. Modifia…

ContextThe concentration of circulating anti-Müllerian hormone (AMH) predicts short-term (3-5 years) bone loss around menopause. Whether AMH during midreproductive years predicts bone health over a decade later is unknown.ObjectiveTo study …

Abstract Study question Is history of laparoscopically-confirmed endometriosis associated with worse cognitive function in middle-aged women? Summary answer History of laparoscopically-confirmed endometriosis is associated with lower cognit…

OBJECTIVE: To investigate the association of soy and isoflavone intake with the risk of laparoscopically confirmed endometriosis. DESIGN: The Nurses' Health Study II, a prospective cohort study from 1991-2021. SUBJECTS: A total of 82,084 …

BACKGROUND: Although endometriosis is a common condition-affecting ∼10% of premenopausal individuals-its etiology is unknown. Diet receives a lot of attention from patients, but studies of the role of diet are limited. Examining dietary pat…

OBJECTIVE: To prospectively assess the effect of endometriosis and uterine fibroids on the long term risk of premature mortality (younger than 70 years). DESIGN: Prospective cohort study SETTING: The Nurses' Health Study II, United States …

OBJECTIVES: To better understand whether history of infertility is associated with anti-Müllerian hormone (AMH) levels later in life, outside of reproduction. METHODS: Among 1,758 premenopausal women in the Nurses' Health Study II with mea…

ObjectiveTo investigate barriers in accessing care for infertility in Mexico, because little is known about this issue for low and middle-income countries, which comprise 80% of the world's population.DesignCross-sectional analysis.SettingM…

ObjectiveTo investigate the association between infertility and the incidence of invasive cancer.DesignProspective cohort study (1989-2015).SettingNot applicable.Patient(s)A total of 103,080 women aged 25-42 years in the Nurses' Health Stud…

BACKGROUND: Women are at greater risk than men of developing chronic inflammatory conditions and "long COVID." However, few gynecologic health risk factors for long COVID-19 have been identified. Endometriosis is a common gynecologic disord…

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identified 43 genomic loci a…

Background Certain symptoms associated with infertility are associated with cardiovascular disease, including menstrual cycle irregularity, early menopause, and obesity; however, few studies have investigated the association between inferti…

ObjectiveTo investigate the association between intake of soy food and isoflavone with ovarian reserve. Previous studies suggest on the relationship between soy intake and human fertility are inconsistent. Some clinical studies suggest that…

Study questionIs there an association between iron intake and ovarian reserve among women seeking fertility care?Summary answerSupplemental iron intake above 45 mg/day is associated with lower ovarian reserve among women seeking fertility c…

BackgroundFertility-awareness-based methods have been linked to shorter time to conception; however, little is known about the predictors of fertility-awareness-based method use among women who are currently or will soon be trying to concei…

BACKGROUND: Infertility has been associated with common chronic non-communicable diseases. However, the association of infertility with long-term mortality is unclear. METHODS: We followed 101,777 women aged 25-42 years at enrollment betwe…

BACKGROUND: The etiology of endometriosis is not well understood. Limited evidence suggests that dietary factors influence risk, but prospective data related to carbohydrate, fiber, and gluten consumption are scarce. Despite this, recommend…

OBJECTIVE: To examine the association between the intake of fruits and vegetables with high- vs. low-pesticide residue burden and diagnosis of laparoscopically confirmed endometriosis. The etiology of endometriosis is not well understood, b…

Purpose(s)To evaluate the relationship of men's dietary patterns with outcomes of in vitro fertilization (IVF).MethodsThis is a prospective cohort study including 231 couples with 407 IVF cycles, presented at an academic fertility center fr…