Gabriela Laste

No ORCID on file · 2 papers in corpus

rct 2015

Combined neuromodulatory interventions in acute experimental pain: assessment of melatonin and non-invasive brain stimulation

Frontiers in behavioral neuroscience ·doi:10.3389/fnbeh.2015.00077

Transcranial direct current stimulation (tDCS) and melatonin can effectively treat pain. Given their potentially complementary mechanisms of action, their combination could have a synergistic effect. Thus, we tested the hypothesis that comp…

rct 2014

Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial

BMC pharmacology & toxicology ·doi:10.1186/2050-6511-15-40

BACKGROUND: Central disinhibition is a mechanism involved in the physiopathology of fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold. We hypothesized that treatment with melatonin alone or in combination with amitr…