Schumacher F

ORCID: 0000-0001-8703-3275 · 2 papers in corpus

article 2026

Sphingosine 1-phosphate-driven interplay between neutrophils and endometriotic cells fuels fibrosis in endometriosis: insights into the role of neutrophil extracellular traps

·doi:10.1186/s12967-026-08971-9

Abstract Background Endometriosis is a chronic disease affecting millions of women worldwide, characterized by the presence of ectopic endometrial-like tissue. While the formation of neutrophil extracellular traps (NETs) has been linked to …

2024

The sphingosine kinase 2 inhibitors ABC294640 and K145 elevate (dihydro)sphingosine 1-phosphate levels in various cells.

Journal of lipid research ·doi:10.1016/j.jlr.2024.100631

Sphingosine kinases (SphKs), enzymes that produce the bioactive lipids dihydrosphingosine 1-phosphate (dhS1P) and sphingosine 1-phosphate (S1P), are associated with various diseases, including cancer and infections. For this reason, a numbe…