H O Critchley

No ORCID on file · 5 papers in corpus
rct 2007
Mifepristone induced progesterone withdrawal reveals novel regulatory pathways in human endometrium
Molecular human reproduction ·doi:10.1093/molehr/gam021

In women, a single dose of the antiprogestin mifepristone (RU486) in the secretory phase rapidly renders the endometrium unreceptive and is followed by endometrial breakdown and menstruation within 72 h. This model provides a system to iden…

observational 2001
Referral for menstrual problems: cross sectional survey of symptoms, reasons for referral, and management
BMJ (Clinical research ed.) ·doi:10.1136/bmj.323.7303.24

OBJECTIVES: To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the …

nonrandomized-trial 2000
Progesterone withdrawal up-regulates vascular endothelial growth factor receptor type 2 in the superficial zone stroma of the human and macaque endometrium: potential relevance to menstruation
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.9.6769

Several reports indicate that vascular endothelial growth factor (VEGF) expression is increased in endometrial glands and stroma during the menstrual phase in the human endometrium. Here we report that VEGF receptor type 2 (KDR), normally e…

review 1996
Prostaglandins and menstruation
European Journal of Obstetrics & Gynecology and Reproductive Biology ·doi:10.1016/s0301-2115(96)02568-7
observational 1994
Endometrial sex steroid receptor expression in women with menorrhagia
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1994.tb11917.x

OBJECTIVE: To investigate the oestrogen and progesterone receptor distribution in endometrium from reproductive age and perimenopausal women with and without menorrhagia. DESIGN: A comparative observational study. SUBJECTS: Forty-five wom…