ABSTRACT Key Content Unexplained infertility accounts for up to 30% of cases of infertility. Potential causes for unexplained infertility have been proposed including reduced oocyte quality, poor endometrial receptivity, ovulatory PCOS, sub…
ObjectiveTo compare the effect of luteal-phase progesterone supplementation in natural cycles to expectant management on live birth rates in women with unexplained infertility (UI).DesignAn open-label, parallel-arm, single-centre randomised…
IntroductionIntrauterine insemination (IUI) is one of the most widespread fertility treatments. However, IUI protocols vary significantly amongst fertility clinics. Various add-on interventions have been proposed to boost success rates. The…
PurposeTo investigate the possibility that altered actions of endogenous progesterone affect receptivity and contribute to unexplained infertility (UI).MethodsTwo authors electronically searched MEDLINE, CINAHL and Embase databases from inc…
Study questionDoes a policy of elective freezing of embryos, followed by frozen embryo transfer result in a higher healthy baby rate, after first embryo transfer, when compared with the current policy of transferring fresh embryos?Summary a…
Study questionWhat is the clinical-effectiveness and safety of the endometrial scratch (ES) procedure compared to no ES, prior to usual first time in vitro fertilisation (IVF) treatment?Summary answerES was safe but did not improve pregnanc…
BackgroundEmbryo incubation and assessment is a vital step in assisted reproductive technology (ART). Traditionally, embryo assessment has been achieved by removing embryos from a conventional incubator daily for quality assessment by an em…
BackgroundEmbryo incubation and assessment is a vital step in assisted reproductive technology (ART). Traditionally, embryo assessment has been achieved by removing embryos from a conventional incubator daily for quality assessment by an em…
ObjectiveTo evaluate the best first line management option for the treatment of unexplained subfertility-controlled ovarian hyperstimulation (COH) with gonadotropins and IUI or IVF.DesignRandomized controlled trial.SettingSingle center tria…