Meng-Horng Lee

No ORCID on file · 3 papers in corpus
lab-animal 2024
Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube
Science advances ·doi:10.1126/sciadv.adp6285

The fallopian tubes play key roles in processes from pregnancy to ovarian cancer where three-dimensional (3D) cellular and extracellular interactions are important to their pathophysiology. Here, we develop a 3D multicompartment assembloid …

lab-animal 2023
Precision-engineered biomimetics: the human fallopian tube
bioRxiv : the preprint server for biology ·doi:10.1101/2023.06.06.543923

UNLABELLED: The fallopian tube has an essential role in several physiological and pathological processes from pregnancy to ovarian cancer. However, there are no biologically relevant models to study its pathophysiology. The state-of-the-art…

lab-animal 2020
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
Nature communications ·doi:10.1038/s41467-020-16416-0

Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidate the mechanisms underlying how ARID1A deleterious mutation contributes to tumorigenesis, we …