BACKGROUND: To investigate the efficacy and safety of a combined oral contraceptive containing estradiol valerate and dienogest (EV/DNG) in healthy Asian women. METHODS: In this multicenter Phase III study, women received oral EV/DNG in a 2…
AIM: The aim of this study was to investigate whether a vegetarian diet correlates with a potential reduced risk of uterine fibroids. MATERIAL AND METHODS: We used data from a case-control study conducted in Southeast University Zhongda Hos…
Uterine leiomyoma (UL) is an estrogen-responsive benign tumor in the female reproductive system and the main risk of hysterectomy for women. However, gene polymorphism of estrogen-metabolizing enzymes may lead to the different susceptibilit…
Published data on the association between the glutathione S-transferases (GSTs) gene polymorphisms and endometriosis risk are inconclusive. We performed a meta-analysis to clarify the association of GSTM1 and GSTT1 polymorphisms and endomet…
Objective To investigate the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD) on development of endometriosis in a mouse model from perspective of molecular mechanism.Methods The endometriosis mouse model was established with autotranspl…