Vitolo MI

ORCID: 0000-0001-8055-9645 · 2 papers in corpus
2022
Microtentacle Formation in Ovarian Carcinoma.
Cancers ·doi:10.3390/cancers14030800

BackgroundThe development of chemoresistance to paclitaxel and carboplatin represents a major therapeutic challenge in ovarian cancer, a disease frequently characterized by malignant ascites and extrapelvic metastasis. Microtentacles (McTNs…

2020
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming.
Nature communications ·doi:10.1038/s41467-020-16416-0

Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin remodeling gene, are prevalent in human endometrium-related malignancies. To elucidate the mechanisms underlying how ARID1A deleterious mutation contributes to tumorigenesis, we …