Jed N Lampe

No ORCID on file · 2 papers in corpus
other 2023
The Journal of biological chemistry ·doi:10.1016/j.jbc.2023.104993

Human fetal cytochrome P450 3A7 (CYP3A7) is involved in both xenobiotic metabolism and the estriol biosynthetic pathway. Although much is understood about cytochrome P450 3A4 and its role in adult drug metabolism, CYP3A7 is poorly character…

review 2019
Archives of biochemistry and biophysics ·doi:10.1016/j.abb.2019.108078

The human cytochrome P450 CYP3A7, once thought to be an enzyme exclusive to fetal livers, has more recently been identified in neonates and developing infants as old as 24 months post-gestational age. CYP3A7 has been demonstrated to metabol…