Rolf W. Hartmann (124550)

No ORCID on file · 1 paper in corpus

article 2016

Lead Optimization of 17β-HSD1\nInhibitors of\nthe (Hydroxyphenyl)naphthol Sulfonamide Type for the Treatment of\nEndometriosis

·doi:10.1021/jm201735j.s001

The reduction of estrone to estradiol, the most potent\nestrogen\nin human, is catalyzed by 17β-hydroxysteroid dehydrogenase type\n1 (17β-HSD1). A promising approach for the treatment of estrogen-dependent\ndiseases is the reduction of intr…