Hamilton KJ

No ORCID on file · 6 papers in corpus · active 2012-2019

Study types

  • article 1
  • review 1

Condition tags

  • endometriosis 2
  • infertility 1
2019
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.201801752

Pausing of RNA polymerase II (Pol II) during early transcription, mediated by the negative elongation factor (NELF) complex, allows cells to coordinate and appropriately respond to signals by modulating the rate of transcriptional pause rel…

article 2017
Endocrinology ·doi:10.1210/en.2017-00562

Endometriosis is a gynecological disease that negatively affects the health of 1 in 10 women. Although more information is known about late stage disease, the early initiation of endometriosis and lesion development is poorly understood. He…

review 2017
Current topics in developmental biology ·doi:10.1016/bs.ctdb.2016.12.005

The hormone estrogen is involved in both female and male reproduction, as well as numerous other biological systems including the neuroendocrine, vascular, skeletal, and immune systems. Therefore, it is also implicated in many different dis…

2014
Reproductive biology ·doi:10.1016/j.repbio.2013.12.002

Estrogen receptors (ERs) play a crucial role in reproduction and normal physiology. The two sub-types of ER (ERα and β) are expressed in various levels in different tissues and selective cell types. Gene targeting technology allowed us to p…

2013
Toxicological sciences : an official journal of the Society of Toxicology ·doi:10.1093/toxsci/kft208

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) given as a cotreatment with estrogen exhibits antiestrogenic properties on the rodent adult uterus, but less is understood regarding hormonal responsiveness of the adult uterus from animals having …

2012
Reproductive toxicology (Elmsford, N.Y.) ·doi:10.1016/j.reprotox.2012.08.005

ERΔ3 transgenic mice expressing a dominant negative estrogen receptor α (ERα) variant lacking the second zinc finger in the DNA binding domain were developed to examine its potential to inhibit estrogen action in vivo. To investigate if ERΔ…