Fraser R

ORCID: 0000-0002-3847-3554 · 2 papers in corpus

2022

Killer Timing: The Temporal Uterine Natural Killer Cell Differentiation Pathway and Implications for Female Reproductive Health.

Frontiers in endocrinology ·doi:10.3389/fendo.2022.904744

Natural killer (NK) cells are the predominant maternal uterine immune cell component, and they densely populate uterine mucosa to promote key changes in the post-ovulatory endometrium and in early pregnancy. It is broadly accepted that (a) …

2021

A 3D endometrial organotypic model simulating the acute inflammatory decidualisation initiation phase with epithelial induction of the key endometrial receptivity marker, integrin αVβ3.

Human reproduction open ·doi:10.1093/hropen/hoab034

Study questionIs it possible to develop a simplified physiological in vitro system representing the key cell-types associated with a receptive endometrial phenotype?Summary answerWe present a new concept to investigate endometrial receptivi…