Levin ER

ORCID: 0000-0003-3015-4177 · 2 papers in corpus · active 2016-2019
2019
The histone methyltransferase EZH2 is required for normal uterine development and function in mice†.
Biology of reproduction ·doi:10.1093/biolre/ioz097

Enhancer of zeste homolog 2 (EZH2) is a rate-limiting catalytic subunit of a histone methyltransferase, polycomb repressive complex, which silences gene activity through the repressive histone mark H3K27me3. EZH2 is critical for epigenetic …

2016
Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors.
Nature reviews. Molecular cell biology ·doi:10.1038/nrm.2016.122

Steroid hormone receptors mediate numerous crucial biological processes and are classically thought to function as transcriptional regulators in the nucleus. However, it has been known for more than 50 years that steroids evoke rapid respon…