Pennell CE

No ORCID on file · 8 papers in corpus · active 2012-2023
2023
Genetic effects on the timing of parturition and links to fetal birth weight.
Nature genetics ·doi:10.1038/s41588-023-01343-9

The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a maternal genome-wide meta-analysis of gestational duration (n = 195,555), identifying 22 associate…

2019
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-019-0447-2

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2019
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.
Nature communications ·doi:10.1038/s41467-019-11881-8

The duration of pregnancy is influenced by fetal and maternal genetic and non-genetic factors. Here we report a fetal genome-wide association meta-analysis of gestational duration, and early preterm, preterm, and postterm birth in 84,689 in…

2018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-017-0011-x

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…

2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-018-0050-y

In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.

2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature genetics ·doi:10.1038/s41588-018-0082-3

In the version of this article originally published, one of the two authors with the name Wei Zhao was omitted from the author list and the affiliations for both authors were assigned to the single Wei Zhao in the author list. In addition, …

2016
Genome-wide associations for birth weight and correlations with adult disease.
Nature ·doi:10.1038/nature19806

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in observational studies is reproducibly associated with future risk of adult metabolic diseases including type 2 diabetes (T2D) and cardiovascular dis…

2012
Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations.
Human molecular genetics ·doi:10.1093/hmg/ddr478

Serum gamma-glutamyl transferase (GGT) activity is a marker of liver disease which is also prospectively associated with the risk of all-cause mortality, cardiovascular disease, type 2 diabetes and cancers. We have discovered novel loci aff…