Zhenbo Chen

No ORCID on file · 1 paper in corpus

lab-animal 2026

GSDME-mediated pyroptosis is essential for the chemotherapeutic effects achieved by combined treatment of temsirolimus and 5-fluorouracil in ovarian carcinoma cells

American journal of translational research ·doi:10.62347/tjwx5574

OBJECTIVES: The expression of GSDMD and GSDME in ovarian cancerous tissues, adjacent tissues, and cancer cell lines remain poorly characterized. The contribution of pyroptosis to the synergistic therapeutic effects of PI3K-AKT-mTOR inhibito…