Tan TZ — Endo Lab

2024

Comprehensive characterization of genomic features and clinical outcomes following targeted therapy and secondary cytoreductive surgery in OCCC: a single center experience.

Journal of gynecologic oncology ·doi:10.3802/jgo.2024.35.e69

ObjectiveOvarian clear cell carcinoma (OCCC) is associated with chemoresistance. Limited data exists regarding the efficacy of targeted therapies such as immune checkpoint inhibitors (ICI) and bevacizumab, and the role of secondary cytoredu…

2020

Identification of serum cytokine clusters associated with outcomes in ovarian clear cell carcinoma.

Scientific reports ·doi:10.1038/s41598-020-75536-1

Serum cytokine and chemokine networks may reflect the complex systemic immunological interactions in cancer patients. Studying groups of cytokines and their networks may help to understand their clinical biology. A total of 178 cases of ova…

2017

'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.

British journal of pharmacology ·doi:10.1111/bph.13958

Recent discoveries in the non-coding genome have challenged the original central dogma of molecular biology, as non-coding RNAs and related processes have been found to be important in regulating gene expression. MicroRNAs and long non-codi…