Mark A. Eckert — Endo Lab

2025

Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types.

Cancer research communications ·doi:10.1158/2767-9764.crc-25-0147

Endometrioid and mucinous ovarian carcinomas represent nearly a fifth of ovarian cancers, but their molecular characteristics and pathologic origins are poorly understood. To identify the genomic and epigenomic alterations characteristic of…

article 2025

Supplementary Figure S11 from Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types

·doi:10.1158/2767-9764.30539520

Kaplan-Meier survival curves for ovarian cancer patients with and without mutations in the PI3K and WNT pathways. (a, b) Alterations in the PI3K pathway trended towards increased survival among patients with ovarian endometrioid carcinomas …

2016

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.

Nature communications ·doi:10.1038/ncomms12645

A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumour of origin at the molecular level, but also demonstrate functional utility in pre-clinical investigations. Here, we report the i…