Fang Xie

目的 基于网络药理学并运用分子对接和动物实验进行验证，平冲降逆方治疗子宫内膜异作症（EMs）的潜在分子机制。 方法 借助TCMSP和BATMAN-TCM 数据库检索平冲降逆方活性成分和作用靶点，并构建“中药-活性成分-靶点”网络。以“endometriosis”为关键词在 Genecards、OMIM和TTD数据库获取疾病靶点。将交集靶点导入 STRING 数据库和 Cytoscape 软件筛选核心治疗靶点，借助 DAVID 数据库进行GO富集分析和KEGG富集分析。利…

BACKGROUND: This study investigates the relationship between the Dietary Inflammation Index (DII) and the risk of infertility among women of childbearing age in the United States. METHODS: This cross-sectional study analyzed data from 3184…

INTRODUCTION: This study investigated whether probiotics alleviate Endometriosis (EMs)-related inflammation by modulating the gut microbiota and short-chain fatty acids (SCFAs). METHODS: An endometriosis model was established in SD rats, w…

MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. We evaluated the levels of family members relative to the internal control miR-103a in ovarian cancer and control blood specimens collected from American and Hong Kong Chi…

RNAs stored in the metaphase II-arrested oocyte play important roles in successful embryonic development. Their abundance is defined by transcriptional activity during oocyte growth and selective degradation of transcripts during LH-induced…

Whether visceral organ cross-sensitization is involved in endometriosis-associated pain remains elusive. Previous studies have shown that visceral noxious stimuli may trigger a cascade of signal transductions in the rostral ventromedial med…

Pelvic organ cross-sensitization, also termed as viscero-visceral referred hyperalgesia, is a major contributor to painful endometriosis. Its underlying mechanism is poorly understood. Clinical and basic studies have shown that gabapentin, …

Objective:To compare the clinical effect of traditional transabdominal hysterectomy(TAH) and modified laparoscopic-assisted transvaginal hysterectomy(MLAVH) in treatment of adenomyosis or large uterine fibroids(uterine≥16 gestational weeks)…