Olympia Kelepouri

article 2022

Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation

eLife ·doi:10.7554/elife.77663

The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis. In this study, we used a mouse model of endometrial repair and…

article 2019

Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus

The Journal of endocrinology ·doi:10.1530/joe-19-0153

Selective androgen receptor modulators (SARMs) have been proposed as therapeutics for women suffering from breast cancer, muscle wasting or urinary incontinence. The androgen receptor (AR) is expressed in the uterus but the impact of SARMs …

other 2018

Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age

Fertility and sterility ·doi:10.1016/j.fertnstert.2017.12.024

OBJECTIVE: To investigate the impact of the androgen precursor dehydroepiandrosterone (DHEA) on the decidualization of human endometrial stromal cells isolated from women of advanced reproductive age. DESIGN: In vitro study. SETTING: Univ…

article 2016

Profiling the decidualisation response of women with endometriosis reveals diverse patterns of steroid responsiveness

·doi:10.1530/endoabs.44.p209

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

article 2016

What is the impact of AR modulation in the decidualisation of hESCs from women with endometriosis?

·doi:10.1530/endoabs.42.oc5

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)