Study types
- article 7
- preprint 2
- other 1
Condition tags
- endometriosis 10
- die_deep_infiltrating 3
- dysmenorrhea 1
- infertility 1
- dyspareunia 1
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other
2024
Background: Deep endometriosis (DE) is a special form of endometriosis, one of the most common benign diseases in gynecology. In the specific case of DE, ectopic endometrium can be found not only in peritoneal but also in deeper tissue laye…
article
2022
Objective Multiple forms of endometriosis have been shown to harbour somatic cancer-driver alterations. Previous studies have focused on the inter-patient heterogeneity of genetic alterations in endometriosis, analyzing lesions collected fr…
article
2022
OBJECTIVE: To investigate the heterogeneity of somatic cancer-driver mutations within patients and across endometriosis types. DESIGN: A single-center cohort, retrospective study. SETTING: Tertiary specialist-care center at a university h…
preprint
2021
Abstract Endometriosis symptoms are heterogeneous with controversy on whether it constitutes a single disease or multiple distinct types. Our previous work found recurrent somatic cancer-driver alterations in endometriosis; however, these h…
article
2020
Endometriosis has yielded controversy on whether it constitutes a single disease or distinct types. Current classification systems poorly correlate with the severity of symptoms and do not provide prognostic tools that can guide management …
article
2019
The advent of next generation sequencing has vastly improved the resolution of mutation detection, thereby both increasing the resolution of the analysis of cancer tissues and shining light on the existence of somatic driver mutations in no…
preprint
2019
Abstract The presence of somatic driver mutations in endometriosis has previously been believed to represent early events in transformation, however our group and others have described such mutations in roughly one-third of cases of deep in…
article
2018
DIE is the most challenging type of endometriosis and may be associated with severe pain and infertility. Complete minimally invasive resection is the gold standard treatment, leading to pain relief and increased fertility in a high number …
article
2018
STUDY QUESTION: Does incisional endometriosis (IE) harbor somatic cancer-driver mutations? SUMMARY ANSWER: We found that approximately one-quarter of IE cases harbor somatic-cancer mutations, which commonly affect components of the MAPK/RAS…
article
2018
DIE is the most challenging type of endometriosis and laparoscopic surgery is considered gold standard. In order to achieve a complete resection extensive surgical procedures have to be performed in the majority of DIE patients. The aim of …