Dotts AJ

No ORCID on file · 1 paper in corpus · active 2021
2021
Progesterone receptor-DNA methylation crosstalk regulates depletion of uterine leiomyoma stem cells: A potential therapeutic target.
Stem cell reports ·doi:10.1016/j.stemcr.2021.07.013

Uterine leiomyoma (LM) is the most common tumor in women. Via its receptor (PGR) expressed in differentiated LM cells, progesterone stimulates paracrine signaling that induces proliferation of PGR-deficient LM stem cells (LSCs). Antiprogest…