C J Lockwood

No ORCID on file · 5 papers in corpus
lab-animal 2010
British journal of cancer ·doi:10.1038/sj.bjc.6605760

BACKGROUND: Uterine serous papillary adenocarcinoma (USPC) is a highly aggressive variant of endometrial cancer. Human immuno-conjugate molecule (hI-con1) is an antibody-like molecule targeted against tissue factor (TF), composed of two hum…

review 2000
Early pregnancy

The abortifacient and menstrual effects of the potent antiprogestin, RU 486 (mifepriston) are associated with both endometrial hemorrhage and extracellular matrix (ECM) degradation. Such processes reflect reduced perivascular decidual cell …

lab-animal 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.1.6292

Perivascular decidualized human endometrial stromal cells (HESCs) are ideally positioned to prevent peri-implantational hemorrhage during endovascular trophoblast invasion by expressing tissue factor (TF), the primary cellular mediator of h…

other 1997
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.82.6.3992

A high incidence of irregular uterine bleeding is the primary patient complaint limiting the utility of long term, progestin-only contraceptive agents such as Norplant. The onset of hemorrhage requires both inadequate hemostasis and impaire…

review 1997
Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.1997.tb48539.x

Progesterone stimulation of the estradiol (E2)-primed human endometrium initiates DZ of the stromal cells around the spiral arterioles. Under continued steroid stimulation, DZ spreads wave-like to establish the decidual cell as a major cell…