Sun Y

Objectives: Although blastocyst transfer may improve embryo selection and early pregnancy outcomes, its impact on live birth in women with recurrent implantation failure (RIF) remains uncertain. This study compared reproductive and perinata…

2,3',4,4',5-Pentachlorobiphenyl (PCB118) is a persistent environmental pollutant associated with adverse female reproductive outcomes; however, its effects on uterine function and epigenetic regulation remain incompletely understood. This s…

Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton. The cytoskeleton is a dynamic network co…

Exogenous gonadotropin-based estrus synchronization is widely used in livestock reproduction. However, this hormonal treatment has been associated with adverse reproductive outcomes, suggesting that it may alter the uterine environment and …

BACKGROUND: Thin endometrium continues to pose a significant challenge in assisted reproductive technology (ART) cycles, necessitating further exploration of therapeutic approaches. Tamoxifen (TMXF) has been primarily used in ovarian stimul…

BACKGROUND: Migraine is a chronic neurological disorder characterized by severe headache, nausea, and sensitivity to light and sound, affecting approximately 1 billion people globally. Despite advances in understanding migraine pathophysiol…

The rapid advances in epigenetic and epitranscriptomic regulatory mechanisms have opened new prospects for precision therapies in various diseases. N-acetyltransferase 10 (NAT10) is currently the only known eukaryotic RNA ac4C acetyltransfe…

PURPOSE: To investigate the impact of regressed endometrial hyperplasia (EH) on assisted reproductive technology outcomes, particularly in comparison with infertile women with a relatively normal endometrium. METHODS: This retrospective st…

BACKGROUND: Obesity is a major global public health concern closely linked to the development and progression of various gynaecological disorders, particularly polycystic ovary syndrome (PCOS) and endometrial cancer. Incretins, a group of g…

Chronic pelvic pain (CPP) is a heterogeneous condition in which visceral, musculoskeletal, neuropathic, and pain-processing contributors often overlap. Pelvic floor ultrasound can depict morphology and movement, but its CPP-specific evidenc…

ETHNOPHARMACOLOGICAL RELEVANCE: Xiao-Liu Tang (XLT), a formulation grounded in the Traditional Chinese medicine (TCM) theory of Qi-Blood, has shown promise in alleviating endometriosis-related symptoms through clinical observations, with em…

We wished to ascertain if there is an association between neutrophil extracellular traps and endometriosis (EMS). We collected the lesional tissues and normal endometrium of 30 patients suffering from endometriosis. Samples were also taken …

OBJECTIVES: Tuberculosis (TB) is a common cause of infertility in humans, especially in regions with high TB prevalence. However, the impact of latent TB infection (LTBI) on pregnancy outcomes following assisted reproduction in patients wit…

BACKGROUND: Previous studies have focused on the effects of ambient air pollutant levels on assisted reproduction. This research focused on the combined effects of lower concentrations of air pollutants and multiple environmental factors on…

Sleep disorders, particularly obstructive sleep apnea (OSA), circadian disruption, and insomnia, are increasingly recognized as contributors to the onset and progression of gynecologic cancers. This review explores the bidirectional interac…

Emerging evidence suggests that gut microbiota imbalances may influence the onset of musculoskeletal disorders (MSDs), yet conclusive evidence establishing causation remains limited. This study investigates the causal relationship between g…

OBJECTIVE: To investigate the determinants affecting live birth outcomes in fresh embryo transfer among polycystic ovary syndrome (PCOS) patients using various machine learning (ML) algorithms and to construct predictive models, offering no…

OBJECTIVE: This study aims to develop a machine learning-based predictive model for patients with endometriosis, with the goal of precisely identifying key factors and reliable predictive markers that influence live birth outcomes following…

PurposeTuberculosis (TB) is a significant factor contributing to infertility. For some infertile patients, chest radiography (CXR) screenings prior to assisted reproductive treatment (ART) reveal old/inactive TB lesions. However, the pregna…

BACKGROUND AND OBJECTIVE: Primary dysmenorrhea carries substantial medical, social, and economic burdens, leading many patients to seek low-risk complementary and alternative therapies, such as acupuncture. Myofascial trigger point dry need…

INTRODUCTION: Chronic pelvic pain (CPP) is a common condition involving multiple systems, characterized by complex manifestations and diverse clinical symptoms. The current treatment options for CPP are limited and may be only effective for…

The production of high-quality oocytes requires precisely orchestrated intercellular communication. Extracellular vesicles (EVs) are cell-derived nanoparticles that play a vital role in the transfer of bioactive molecules, which has gained …

Formononetin (FMN) is a common natural metabolite that can be extracted and isolated from some common botanical drugs. In recent years, FMN has garnered increasing attention due to its beneficial biological activities. In this paper, we sys…

BACKGROUND: To compare the clinical outcomes between frozen-thawed cleavage embryo transfer and frozen-thawed day 6 blastocyst transfer in patients younger than 35 using the freeze-all strategy without day 5 blastocyst formation. METHODS: …

As one of the three major malignant tumors in women, the morbidity of endometrial cancer is second only to that of cervical cancer and is increasing yearly. Its etiological mechanism is not clear, and the risk factors are numerous and commo…