Ronald D. Wiehle

No ORCID on file · 4 papers in corpus · active 2010-2012

Study types

  • article 2
  • book-chapter 2

Condition tags

  • endometriosis 3
book-chapter 2012
Progesterone Receptor Modulators Induce Apoptosis in Mammary Tumors and Uterine Leiomyomas
·doi:10.1007/978-94-007-4917-7_8
article 2011
Population Pharmacokinetics of Telapristone (CDB-4124) and its Active Monodemethylated Metabolite CDB-4453, with a Mixture Model for Total Clearance
The AAPS journal ·doi:10.1208/s12248-011-9304-7

Telapristone is a selective progesterone antagonist that is being developed for the long-term treatment of symptoms associated with endometriosis and uterine fibroids. The population pharmacokinetics of telapristone (CDB-4124) and CDB-4453 …

article 2010
CDB-4124, a Progesterone Receptor Modulator, Inhibits Mammary Carcinogenesis by Suppressing Cell Proliferation and Inducing Apoptosis
Cancer prevention research (Philadelphia, Pa.) ·doi:10.1158/1940-6207.capr-10-0244

CDB-4124 (Proellex or telapristone acetate) is a modulator of progesterone receptor (PR) signaling, which is currently employed in preclinical studies for prevention and treatment of breast cancer and has been used in clinical studies for t…

book-chapter 2010
Progesterone Receptor Modulators in Endometriosis: A New Therapeutic Option
·doi:10.5005/jp/books/11032_27