Chenyang Huang

ORCID: 0000-0002-1956-6229 · 30 papers in corpus
lab-animal 2018
Increased Krüppel-like factor 12 impairs embryo attachment via downregulation of leukemia inhibitory factor in women with recurrent implantation failure
Cell death discovery ·doi:10.1038/s41420-018-0088-8

Recurrent implantation failure (RIF) caused by various etiological factors remains a challenge for fertility clinicians using assisted reproductive technology (ART) worldwide. Dysregulation of leukemia inhibitory factor (LIF) in the endomet…

lab-animal 2017
Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0260-7

BACKGROUND: A receptive endometrium is essential for maternal-embryonic molecular communication during implantation. However, the specific molecular regulatory mechanisms of the endometrial capacity remain poorly understood. Here, we examin…

2017
CAPN7 negatively regulates embryo adhesion via cleaving hoxa10
·doi:10.1016/j.fertnstert.2017.07.629
lab-animal 2017
Enhanced HOXA10 sumoylation inhibits embryo implantation in women with recurrent implantation failure
Cell death discovery ·doi:10.1038/cddiscovery.2017.57

HOXA10 has emerged as an important molecular marker of endometrial receptivity. Recurrent implantation failure (RIF) after in vitro fertilization-embryo transplantation (IVF-ET) treatment is associated with impaired endometrial receptivity,…

lab-animal 2017
Increased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-017-0243-8

BACKGROUND: Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal cells (hESCs), Krüp…