Cass I

No ORCID on file · 4 papers in corpus · active 2018-2022

Study types

  • preprint 2
  • meta-analysis 1

Condition tags

  • endometriosis 3
  • endometrioma 1
  • die_deep_infiltrating 1
meta-analysis 2022
A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes
Cell reports. Medicine ·doi:10.1016/j.xcrm.2022.100542

Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using data from large endometriosis and EOC genome-wide association meta-analyses, we estimate the genetic correlation and evaluate the causal relationshi…

preprint 2021
A cellular and molecular portrait of endometriosis subtypes
·doi:10.1101/2021.05.20.445037

Abstract Endometriosis is a common, benign condition characterized by extensive heterogeneity in lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual cells from endometriomata (n=7), extra-ovarian endomet…

preprint 2021
A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes
·doi:10.1101/2021.06.28.21259290

Abstract Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Data from large endometriosis and EOC genome-wide association meta-analyses were used to estimate the genetic correlation and evaluate the causal…

2018
Aspirin use correlates with survival in women with clear cell ovarian cancer.
Gynecologic oncology reports ·doi:10.1016/j.gore.2018.06.004

Data from colon, breast and prostate cancers suggest that aspirin users have reduced mortality. While the direct mechanism remains uncertain, aspirin can suppress the COX-dependent and independent pathways involved in tumor progression. We …