Astrid Marie Kolte

meta-analysis 2024

Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage

Nature genetics ·doi:10.1038/s41588-024-01839-y

Bleeding in early pregnancy and postpartum hemorrhage (PPH) bear substantial risks, with the former closely associated with pregnancy loss and the latter being the foremost cause of maternal death, underscoring the severe impact on maternal…

observational 2024

Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study

BMC medicine ·doi:10.1186/s12916-024-03797-y

BACKGROUND: Pregnancy is a complex biological process and serious complications can arise when the delicate balance between the maternal and semi-allogeneic fetal immune systems is disrupted or challenged. Gestational diabetes mellitus (GDM…

guideline 2023

ESHRE guideline: recurrent pregnancy loss: an update in 2022

Human reproduction open ·doi:10.1093/hropen/hoad002

STUDY QUESTION: What are the updates for the recommended management of women with recurrent pregnancy loss (RPL) based on the best available evidence in the literature from 2017 to 2022? SUMMARY ANSWER: The guideline development group (GDG…

2023

Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage

·doi:10.1101/2023.08.10.23293932

Bleeding in early pregnancy and postpartum hemorrhage (PPH) bear substantial risks, with the former closely associated with pregnancy loss and the latter being the foremost cause of maternal death, underscoring the severity of these complic…