Neoptolemos JP

ORCID: 0000-0002-6201-7399 · 2 papers in corpus

2020

Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis.

Cell death & disease ·doi:10.1038/s41419-020-03050-3

Chronic pancreatitis (CP) is associated with elevated plasma levels of bacterial lipopolysaccharide (LPS) and we have demonstrated reduced acinar cell autophagy in human CP tissue. Therefore, we investigated the role of autophagy in experim…

2015

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-14-2467

PurposeNoninvasive biomarkers for early detection of pancreatic ductal adenocarcinoma (PDAC) are currently not available. Here, we aimed to identify a set of urine proteins able to distinguish patients with early-stage PDAC from healthy ind…