Boqun Liu

No ORCID on file · 4 papers in corpus
other 2023
Biomarkers identification in follicular fluid of women with OHSS by using UPLC-MS method
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1131771

To figure out the differentially changed metabolites and disturbed pathways in follicular fluid (FF) of patients with OHSS in comparison to the control group undergoing in vitro fertilization (IVF), we conducted this metabolomic analysis be…

lab-animal 2023
TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome
Cell communication and signaling : CCS ·doi:10.1186/s12964-023-01123-2

BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is a serious complication during in vitro fertilization (IVF) treatment. The upregulation of ovarian transforming growth factor-beta 1 (TGF-β1) is involved in the development of OHSS. The…

lab-animal 2022
Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00912-7

BACKGROUND: Growth differentiation factor-11 (GDF-11) belongs to the transforming growth factor-β (TGF-β) superfamily. To date, the expression of GDF-11 in the ovary and its role in regulating ovarian function are completely unknown. Ovaria…

lab-animal 2021
High ovarian GDF-8 levels contribute to elevated estradiol production in ovarian hyperstimulation syndrome by stimulating aromatase expression
International journal of biological sciences ·doi:10.7150/ijbs.60332

Rationale: Growth differentiation factor-8 (GDF-8), also known as myostatin, belongs to the transforming growth factor-beta (TGF-β) superfamily. GDF-8 is expressed in the ovary and regulates various ovarian functions. Ovarian hyperstimulati…