Joseph C. Chen

ORCID: 0000-0003-3855-2479 · 3 papers in corpus · active 2014-2020

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 3
  • infertility 1
other 2020
Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling
Human Reproduction ·doi:10.1093/humrep/deaa015

STUDY QUESTION: Do seminal plasma (SP) and its constituents affect the decidualization capacity and transcriptome of human primary endometrial stromal fibroblasts (eSFs)? SUMMARY ANSWER: SP promotes decidualization of eSFs from women with …

article 2016
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis1
Biology of reproduction ·doi:10.1095/biolreprod.115.136010

Human endometrium undergoes cyclic regeneration involving stem/progenitor cells, but the role of resident endometrial mesenchymal stem cells (eMSC) as progenitors of endometrial stromal fibroblasts (eSF) has not been definitively demonstrat…

article 2014
Inhibition of epidermal growth factor receptor restores decidualization markers in stromal fibroblasts from women with endometriosis
·doi:10.5301/je.5000198

Purpose Decidualization comprises specific biochemical and morphological changes in uterine endometrium essential for establishment of pregnancy. This process is abnormal in women with endometriosis, a disorder in which endometrial-like tis…