Esther M. John — Endo Lab

2025

Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2.

Journal of Clinical Oncology ·doi:10.1200/jco.24.00176

PurposeIt is uncertain whether, and to what extent, hormonal contraceptives increase breast cancer (BC) risk for germline BRCA1 or BRCA2 mutation carriers.MethodsUsing pooled observational data from four prospective cohort studies, associat…

2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Nature genetics ·doi:10.1038/ng.3826

To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptib…

article 2015

Evidence of a genetic link between endometriosis and ovarian cancer

Fertility and sterility ·doi:10.1016/j.fertnstert.2015.09.023

ObjectiveTo evaluate whether endometriosis-associated genetic variation affects risk of ovarian cancer.DesignPooled genetic analysis.SettingUniversity hospital.Patient(s)Genetic data from 46,176 participants (15,361 ovarian cancer cases and…

article 2015

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

Human molecular genetics ·doi:10.1093/hmg/ddv306

Epidemiological studies have demonstrated associations between endometriosis and certain histotypes of ovarian cancer, including clear cell, low-grade serous and endometrioid carcinomas. We aimed to determine whether the observed associatio…

article 2015

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

Epidemiological studies have demonstrated associations between endometriosis and certain histotypes of ovarian cancer, including clear cell, low-grade serous and endometrioid carcinomas. We aimed to determine whether the observed associatio…