Merja R. Häkkinen

ORCID: 0000-0002-7793-1781 · 2 papers in corpus · active 2014-2018

Study types

  • article 1
  • other 1

Condition tags

  • mesh:D004715 1
  • endometriosis 1
other 2018
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue
Journal of pharmaceutical and biomedical analysis ·doi:10.1016/j.jpba.2018.01.034

An LC-MS/MS method was developed and validated to analyze simultaneously estrogens (estradiol, E2; estrone, E1), androgens (testosterone, T; androstenedione, A4; dehydroepiandrosterone, DHEA), progestagens (17a-hydroxypregnenolone, 17OHP5; …

article 2014
Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2014-1913

Aberrant sex steroid signaling is suggested to promote endometriosis growth by several mechanisms, and the tissue concentrations of sex steroids are key determinants of the hormone action. However, their concentrations are only superficiall…