Sellers ZM

ORCID: 0000-0001-5352-7760 · 2 papers in corpus

2023

Notch signaling inactivation by small molecule γ-secretase inhibitors restores the multiciliated cell population in the airway epithelium.

American journal of physiology. Lung cellular and molecular physiology ·doi:10.1152/ajplung.00382.2022

Multiciliated cell loss is a hallmark of airway epithelial remodeling in chronic inflammatory airway diseases including cystic fibrosis (CF), asthma, and chronic obstructive pulmonary disease. It disrupts mucociliary clearance, which fuels …

2022

Current clinical opinion on CFTR dysfunction and patient risk of pancreatitis: diagnostic and therapeutic considerations.

Expert review of gastroenterology & hepatology ·doi:10.1080/17474124.2022.2084072

IntroductionCystic fibrosis transmembrane conductance regulator (CFTR)-mediated chloride and bicarbonate secretion is integral to the pancreas' ability to produce the alkaline pancreatic juice required for proper activation of enzymes for d…