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INTRODUCTION: Evidence increasingly shows small nerve fibre pathology in subsets of people with fibromyalgia through skin biopsy, corneal confocal microscopy, and microneurography. However, blood-based biomarkers of ongoing neuronal damage,…

Sleep problems commonly coexist with chronic pain conditions, with growing evidence that they may precede and contribute to pain persistence. Meanwhile, pain itself can disturb sleep, creating a bidirectional relationship. In this narrative…