Velu SE

ORCID: 0000-0002-0342-2378 · 1 paper in corpus

2017

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.

Scientific reports ·doi:10.1038/s41598-017-06168-1

Streptococcus mutans employs a key virulence factor, three glucosyltransferase (GtfBCD) enzymes to establish cariogenic biofilms. Therefore, the inhibition of GtfBCD would provide anti-virulence therapeutics. Here a small molecule library o…